Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.47 |
| ▸ | BRD2 | P25440 | 2/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.47 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389571 | 0.87 | BRD4 (0.46) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL19090321 | 0.87 | BRD4 (0.46) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL23731052 | 0.86 | BRD4 (0.57) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL21389562 | 0.85 | MAPT (0.45) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL19090322 | 0.82 | BRD4 (0.51) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL19090319 | 0.82 | BRD4 (0.46) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL21389530 | 0.74 | BRD4 (0.56) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL21389588 | 0.74 | BRD4 (0.56) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL19090314 | 0.74 | BRD4 (0.56) | BRD4BRD2BRD3BRDTALDH1A1 | |
| SCHEMBL23731023 | 0.73 | BRD4 (0.55) | BRD4BRD2BRD3BRDTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397640-B1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INST NAT SANTE RECH MED (FR) | 2021-08-04 | — | — | EP | disclosed |