Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | BRD2 | P25440 | 2/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | TPH2 | Q8IWU9 | 13/20 | 0.37 |
| ▸ | TPH1 | P17752 | 12/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23730763 | 0.88 | MEN1 (0.41) | MEN1KMT2ABRD4BRD2BRD3 | |
| SCHEMBL21389567 | 0.75 | MEN1 (0.47) | MEN1KMT2ABRD4BRD2BRD3 | |
| SCHEMBL21389557 | 0.74 | MEN1 (0.47) | MEN1KMT2ABRD4BRD2BRD3 | |
| SCHEMBL21389579 | 0.70 | MEN1 (0.66) | MEN1KMT2ABRD4BRD2BRD3 | |
| SCHEMBL21389578 | 0.70 | MEN1 (0.83) | MEN1KMT2ABRD4BRD2BRD3 | |
| SCHEMBL21389565 | 0.69 | KMT2A (0.56) | MEN1KMT2ABRD4BRD2BRD3 | |
| SCHEMBL19090400 | 0.68 | KMT2A (0.47) | MEN1KMT2ABRD4BRD2BRD3 | |
| SCHEMBL21389560 | 0.68 | MEN1 (0.51) | MEN1KMT2ABRD4BRD2BRD3 | |
| SCHEMBL21389505 | 0.68 | BRD4 (0.46) | MEN1KMT2ABRD4BRD2BRD3 | |
| SCHEMBL21389585 | 0.68 | KMT2A (0.53) | MEN1KMT2ABRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397640-B1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INST NAT SANTE RECH MED (FR) | 2021-08-04 | — | — | EP | disclosed |