Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRD2 | P25440 | 2/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.36 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23730767 | 0.88 | MEN1 (0.44) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL19090402 | 0.74 | MEN1 (0.42) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL19090399 | 0.73 | MEN1 (0.42) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL19090588 | 0.69 | TPH1 (0.47) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL19090391 | 0.66 | MEN1 (0.45) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL19090392 | 0.66 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL19066322 | 0.66 | RXFP1 (0.59) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL19066314 | 0.66 | MEN1 (0.65) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL19090589 | 0.66 | MAPT (0.49) | MEN1KMT2AALDH1A1GAANPSR1 | |
| SCHEMBL19090586 | 0.65 | KDM4E (0.49) | MEN1KMT2AALDH1A1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397640-B1 | XANTHINE DERIVATIVE INHIBITORS OF BET PROTEINS | INST NAT SANTE RECH MED (FR) | 2021-08-04 | — | — | EP | disclosed |