Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24168607 | 0.88 | NTRK1 (0.68) | NTRK1JAK2 | |
| SCHEMBL21911502 | 0.87 | NTRK1 (0.55) | NTRK1JAK2 | |
| SCHEMBL23732307 | 0.86 | NTRK1 (0.54) | NTRK1JAK2 | |
| SCHEMBL21911083 | 0.86 | NTRK1 (0.54) | NTRK1JAK2 | |
| SCHEMBL23732305 | 0.85 | NTRK1 (0.67) | NTRK1JAK2 | |
| SCHEMBL24168768 | 0.83 | NTRK1 (0.51) | NTRK1JAK2 | |
| SCHEMBL21911085 | 0.79 | NTRK1 (0.70) | NTRK1JAK2 | |
| SCHEMBL21911084 | 0.78 | NTRK1 (0.56) | NTRK1JAK2 | |
| SCHEMBL2695396 | 0.78 | NTRK1 (1.00) | NTRK1JAK2 | |
| SCHEMBL15891071 | 0.78 | NTRK1 (1.00) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858834-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE AS SELECTIVE TRK INHIBITOR | Shandong Luye Pharmaceutical Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |