Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.67 |
| ▸ | INSR | P06213 | 5/20 | 0.67 |
| ▸ | LCK | P06239 | 4/20 | 0.67 |
| ▸ | KDR | P35968 | 4/20 | 0.67 |
| ▸ | KIT | P10721 | 3/20 | 0.67 |
| ▸ | AURKA | O14965 | 2/20 | 0.67 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.67 |
| ▸ | LYN | P07948 | 2/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.67 |
| ▸ | SRC | P12931 | 2/20 | 0.67 |
| ▸ | FLT1 | P17948 | 2/20 | 0.67 |
| ▸ | FLT4 | P35916 | 2/20 | 0.67 |
| ▸ | FLT3 | P36888 | 2/20 | 0.67 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.67 |
| ▸ | PLK4 | O00444 | 1/20 | 0.67 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.67 |
| ▸ | CSF1R | P07333 | 1/20 | 0.67 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.67 |
| ▸ | MARK3 | P27448 | 1/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28982298 | 1.00 | IGF1R (0.67) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL31327277 | 1.00 | IGF1R (0.67) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL31327268 | 1.00 | IGF1R (0.67) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL23732739 | 1.00 | IGF1R (0.67) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL31327275 | 0.98 | IGF1R (0.69) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL23732413 | 0.98 | IGF1R (0.69) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL28982312 | 0.98 | IGF1R (0.69) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL23732453 | 0.94 | IGF1R (0.60) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL31327290 | 0.94 | IGF1R (0.60) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL23703560 | 0.93 | IGF1R (0.59) | IGF1RINSRLCKKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916966-A | STRAD binding agents and uses thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |