Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.67 |
| ▸ | INSR | P06213 | 5/20 | 0.67 |
| ▸ | LCK | P06239 | 4/20 | 0.67 |
| ▸ | KDR | P35968 | 4/20 | 0.67 |
| ▸ | KIT | P10721 | 3/20 | 0.67 |
| ▸ | AURKA | O14965 | 2/20 | 0.67 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.67 |
| ▸ | LYN | P07948 | 2/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.67 |
| ▸ | SRC | P12931 | 2/20 | 0.67 |
| ▸ | FLT1 | P17948 | 2/20 | 0.67 |
| ▸ | FLT4 | P35916 | 2/20 | 0.67 |
| ▸ | FLT3 | P36888 | 2/20 | 0.67 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.67 |
| ▸ | PLK4 | O00444 | 1/20 | 0.67 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.67 |
| ▸ | CSF1R | P07333 | 1/20 | 0.67 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.67 |
| ▸ | MARK3 | P27448 | 1/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28982298 | 1.00 | IGF1R (0.67) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL31327277 | 1.00 | IGF1R (0.67) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL23732435 | 1.00 | IGF1R (0.67) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL23732739 | 1.00 | IGF1R (0.67) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL31327275 | 0.98 | IGF1R (0.69) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL23732413 | 0.98 | IGF1R (0.69) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL28982312 | 0.98 | IGF1R (0.69) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL23732453 | 0.94 | IGF1R (0.60) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL31327290 | 0.94 | IGF1R (0.60) | IGF1RINSRLCKKDRKIT | |
| SCHEMBL23703560 | 0.93 | IGF1R (0.59) | IGF1RINSRLCKKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195490-B2 | STRAD-binding agents and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195490-B2 | STRAD-binding agents and uses thereof | STRAP, STRA6, PLAUR | IGF1R 1979/4885INSR 2388/4885LCK 2834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.