Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 13/20 | 0.46 |
| ▸ | SRC | P12931 | 6/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | ABL2 | P42684 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.43 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CSK | P41240 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23732775 | 0.88 | EGFR (0.48) | EIF2AK3SRCEGFRABL1ABL2 | |
| SCHEMBL23732436 | 0.86 | BRD4 (0.56) | EIF2AK3SRCEGFRABL1ABL2 | |
| SCHEMBL23732491 | 0.85 | EIF2AK3 (0.47) | EIF2AK3SRCEGFRABL1ABL2 | |
| SCHEMBL23732738 | 0.81 | EIF2AK3 (0.47) | EIF2AK3SRCEGFRABL1ABL2 | |
| SCHEMBL30049558 | 0.81 | IGF1R (0.71) | SRCEGFRABL1LCKIGF1R | |
| SCHEMBL28982313 | 0.81 | IGF1R (0.71) | SRCEGFRABL1LCKIGF1R | |
| SCHEMBL23732599 | 0.81 | IGF1R (0.71) | SRCEGFRABL1LCKIGF1R | |
| SCHEMBL23732944 | 0.81 | EIF2AK3 (0.46) | EIF2AK3SRCEGFRABL1ABL2 | |
| SCHEMBL23732809 | 0.79 | IGF1R (0.54) | EIF2AK3SRCEGFRABL1ABL2 | |
| SCHEMBL23732492 | 0.78 | EIF2AK3 (0.47) | EIF2AK3SRCEGFRABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |