Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2437001 | 0.92 | RIPK1 (0.61) | RIPK1EIF2AK3 | |
| SCHEMBL868811 | 0.83 | RIPK1 (0.83) | RIPK1EIF2AK3 | |
| SCHEMBL868611 | 0.78 | RIPK1 (0.67) | RIPK1EIF2AK3 | |
| SCHEMBL869188 | 0.77 | RIPK1 (0.82) | RIPK1EIF2AK3 | |
| SCHEMBL868494 | 0.76 | RIPK1 (1.00) | RIPK1EIF2AK3 | |
| SCHEMBL2374039 | 0.74 | RIPK1 (0.52) | RIPK1EIF2AK3 | |
| SCHEMBL13861268 | 0.74 | RIPK1 (0.61) | RIPK1EIF2AK3 | |
| SCHEMBL869179 | 0.73 | EIF2AK3 (0.60) | RIPK1EIF2AK3 | |
| SCHEMBL868578 | 0.73 | RIPK1 (0.81) | RIPK1EIF2AK3 | |
| SCHEMBL16341477 | 0.72 | RIPK1 (0.80) | RIPK1EIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2549868-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2013-01-30 | — | — | EP | claimed |
| WO-2011119663-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | claimed |
| EP-2549868-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2013-01-30 | — | — | EP | disclosed |