Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 10/20 | 0.65 |
| ▸ | EGFR | P00533 | 8/20 | 0.65 |
| ▸ | ABL1 | P00519 | 7/20 | 0.65 |
| ▸ | ABL2 | P42684 | 6/20 | 0.65 |
| ▸ | CDK1 | P06493 | 3/20 | 0.65 |
| ▸ | KDR | P35968 | 3/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.57 |
| ▸ | PRKDC | P78527 | 2/20 | 0.57 |
| ▸ | HCK | P08631 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.57 |
| ▸ | EIF2AK3 | Q9NZJ5 | 6/20 | 0.52 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.52 |
| ▸ | EIF2AK1 | Q9BQI3 | 2/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057974 | 0.85 | PIK3CD (0.73) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL23732809 | 0.83 | IGF1R (0.54) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL16202367 | 0.83 | SRC (0.67) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL30388001 | 0.82 | PIK3CD (0.61) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL23732436 | 0.81 | BRD4 (0.56) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL14050381 | 0.81 | IGF1R (0.72) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL23732492 | 0.80 | EIF2AK3 (0.47) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL23732944 | 0.80 | EIF2AK3 (0.46) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL18521763 | 0.79 | SRC (0.71) | SRCEGFRABL1ABL2CDK1 | |
| SCHEMBL23732775 | 0.79 | EGFR (0.48) | SRCEGFRABL1ABL2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |