Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 4/20 | 0.48 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.45 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.45 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | HEXA | P06865 | 1/20 | 0.40 |
| ▸ | HEXB | P07686 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20899594 | 0.83 | MAPKAPK2 (0.57) | ATRMAPKAPK2 | |
| SCHEMBL5960151 | 0.79 | ATR (0.50) | ATRACVR2ATGFBR2NOS1MAPKAPK2 | |
| SCHEMBL12198520 | 0.78 | ATR (0.49) | ATRACVR2ATGFBR2NOS1MAPKAPK2 | |
| SCHEMBL23732500 | 0.78 | ATR (0.50) | ATRACVR2ATGFBR2NOS1KDM4E | |
| SCHEMBL24248209 | 0.75 | ATR (0.39) | ATRACVR2ATGFBR2MAPKAPK2LRRK2 | |
| SCHEMBL12198422 | 0.75 | ATR (0.48) | ATRACVR2ATGFBR2NOS1KDM4E | |
| SCHEMBL23703155 | 0.74 | ATR (0.64) | ATRACVR2ATGFBR2 | |
| SCHEMBL24549472 | 0.73 | MAPKAPK2 (0.59) | ATRMAPKAPK2MAP4K4 | |
| SCHEMBL18895999 | 0.73 | ATR (0.64) | ATRACVR2ATGFBR2 | |
| SCHEMBL23703073 | 0.73 | ATR (0.67) | ATRACVR2ATGFBR2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |