Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.47 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372921 | 1.00 | SLC18A3 (0.47) | SLC18A3MAN2B1HTR6LSSCA12 | |
| SCHEMBL9980744 | 0.82 | SLC18A3 (0.55) | SLC18A3HTR6 | |
| SCHEMBL31209576 | 0.79 | HTR6 (0.48) | MAN2B1HTR6CA12CA1CA2 | |
| SCHEMBL31209245 | 0.79 | HTR6 (0.48) | MAN2B1HTR6CA12CA1CA2 | |
| SCHEMBL2372917 | 0.74 | HRH3 (0.39) | MAN2B1HTR6CA12CA1CA2 | |
| SCHEMBL1085321 | 0.74 | HRH3 (0.39) | MAN2B1HTR6CA12CA1CA2 | |
| SCHEMBL2385937 | 0.73 | HTR6 (0.36) | HTR6CA12CA1CA2CA9 | |
| SCHEMBL9980920 | 0.71 | SLC18A3 (0.56) | SLC18A3KCNH2 | |
| SCHEMBL23553034 | 0.71 | SLC18A3 (0.46) | SLC18A3 | |
| SCHEMBL24458815 | 0.69 | SLC18A3 (0.43) | SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |