Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 7/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
| ▸ | DRD5 | P21918 | 1/20 | 0.58 |
| ▸ | HTR1D | P28221 | 1/20 | 0.58 |
| ▸ | HTR1E | P28566 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712155 | 0.86 | HTR1F (0.70) | HTR1FHTR2CCHRM5DRD5HTR1D | |
| SCHEMBL21712174 | 0.83 | HTR1F (0.65) | HTR1FHTR2CCHRM5DRD5HTR1D | |
| SCHEMBL23733275 | 0.78 | MEN1 (0.62) | HTR1FHTR2CCHRM5DRD5HTR1D | |
| SCHEMBL13270112 | 0.77 | IRAK4 (0.41) | HTR1FHTR2CCHRM5DRD5HTR1D | |
| SCHEMBL23733250 | 0.75 | HTR1F (0.61) | HTR1FHTR2CCHRM5DRD5HTR1D | |
| SCHEMBL28807271 | 0.75 | HTR1F (0.79) | HTR1FHTR2CCHRM5DRD5HTR1D | |
| SCHEMBL23702725 | 0.74 | HTR1F (0.60) | HTR1FHTR2CCHRM5DRD5HTR1D | |
| SCHEMBL29031439 | 0.74 | HTR1F (0.73) | HTR1FHTR2CCHRM5DRD5HTR1D | |
| SCHEMBL4083187 | 0.74 | SMN1; SMN2 (0.58) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL13903425 | 0.74 | HTR2C (0.42) | HTR2CNPC1RAB9AUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021152462-A1 | PROCESS FOR PREPARATION OF LASMIDITAN | GLENMARK LIFE SCIENCES LIMITED (IN) | 2021-08-05 | — | — | WO | disclosed |