Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 18/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23283045 | 0.87 | P2RY12 (0.47) | P2RY12SLC2A1RORC | |
| SCHEMBL23074502 | 0.80 | MAPK1 (0.48) | P2RY12SLC2A1 | |
| SCHEMBL24835211 | 0.79 | P2RY12 (0.47) | P2RY12SLC2A1 | |
| SCHEMBL30778005 | 0.74 | P2RY12 (0.47) | P2RY12SLC2A1 | |
| SCHEMBL23064283 | 0.74 | P2RY12 (0.47) | P2RY12SLC2A1 | |
| SCHEMBL23074480 | 0.73 | P2RY12 (0.48) | P2RY12 | |
| SCHEMBL23064356 | 0.73 | RORC (0.42) | P2RY12SLC2A1RORC | |
| SCHEMBL23064353 | 0.73 | RORC (0.42) | P2RY12SLC2A1RORC | |
| SCHEMBL30778002 | 0.73 | RORC (0.42) | P2RY12SLC2A1RORC | |
| SCHEMBL23283055 | 0.73 | ABL1 (0.48) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548882-B2 | Benzisoxazole compound | OSAKA UNIVERSITY (JP) | 2023-01-10 | — | — | US | disclosed |
| US-20210238171-A1 | BENZISOXAZOLE COMPOUND | INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTES OF NATURAL SCIENCES (JP) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238171-A1 | BENZISOXAZOLE COMPOUND | CBR1, CYP2S1, CYP2E1 | P2RY12 1892/4885SLC2A1 1220/4885RORC 1011/4885 |
| US-11548882-B2 | Benzisoxazole compound | CBR1, CYP2S1, CYP2E1 | P2RY12 1892/4885SLC2A1 1220/4885RORC 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.