Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23283038 | 0.89 | TRPV1 (0.39) | TRPV1MAPTSCDSCD5HSD11B1 | |
| SCHEMBL23701853 | 0.87 | SCD (0.43) | TRPV1MAPTSCDSCD5RORC | |
| SCHEMBL31050097 | 0.85 | MAPT (0.37) | TRPV1MAPTSCDSCD5RORC | |
| SCHEMBL30186170 | 0.85 | MAPT (0.37) | TRPV1MAPTSCDSCD5RORC | |
| SCHEMBL23064279 | 0.85 | MAPT (0.37) | TRPV1MAPTSCDSCD5RORC | |
| SCHEMBL23064280 | 0.85 | MAPT (0.37) | TRPV1MAPTSCDSCD5RORC | |
| SCHEMBL23064379 | 0.85 | MAPT (0.37) | TRPV1MAPTSCDSCD5RORC | |
| SCHEMBL23074511 | 0.77 | MAPT (0.38) | TRPV1MAPTPDK4TDP1 | |
| SCHEMBL23283041 | 0.72 | TRPV1 (0.40) | TRPV1MAPTRORC | |
| SCHEMBL23064245 | 0.69 | ALDH1A1 (0.48) | MAPTSCDSCD5PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3789383-B1 | INHIBITORS OF THE TRPC3 OR TRPC6 CHANNEL | UNIV OSAKA (JP) | 2023-11-29 | — | — | EP | disclosed |
| US-11548882-B2 | Benzisoxazole compound | OSAKA UNIVERSITY (JP) | 2023-01-10 | — | — | US | disclosed |
| US-20210238171-A1 | BENZISOXAZOLE COMPOUND | INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTES OF NATURAL SCIENCES (JP) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238171-A1 | BENZISOXAZOLE COMPOUND | CBR1, CYP2S1, CYP2E1 | TRPV1 2978/4885MAPT 4874/4885SCD 4229/4885 |
| US-11548882-B2 | Benzisoxazole compound | CBR1, CYP2S1, CYP2E1 | TRPV1 2978/4885MAPT 4874/4885SCD 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.