SCHEMBL23733261

SCHEMBL23733261

CO/C=C(/C(=O)OC)c1cc(S)ccc1C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8359584 0.84 MEN1 (0.41) MEN1KMT2A
SCHEMBL8359585 0.84 MEN1 (0.41) MEN1KMT2A
SCHEMBL23712859 0.83 CA12 (0.44) MEN1KMT2A
SCHEMBL23712694 0.82 NPC1 (0.35) MEN1KMT2A
SCHEMBL23712868 0.82 MEN1 (0.31) MEN1KMT2A
SCHEMBL26714248 0.82 NPC1 (0.45) MEN1KMT2A
SCHEMBL23712595 0.82 ALDH1A1 (0.39) MEN1KMT2A
SCHEMBL23712566 0.81 FOLH1 (0.35) MEN1KMT2A
SCHEMBL25469133 0.81 HDAC8 (0.44)
SCHEMBL26717199 0.81 NPC1 (0.35) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021153786-A1 PHENYLACETIC ACID DERIVATIVE, USE THEREFOR, AND PRODUCTION INTERMEDIATE THEREOF 住友化学株式会社 2021-08-05 WO disclosed