SCHEMBL23733386

SCHEMBL23733386

O=CCOCCOCCNC(=O)CCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.58
▸ NOD1 Q9Y239 3/20 0.46
▸ FOLH1 Q04609 6/20 0.43
▸ EPHX2 P34913 1/20 0.43
▸ GLO1 Q04760 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27408102 1.00 GLP1R (0.58) GLP1RNOD1FOLH1EPHX2GLO1
SCHEMBL27407839 0.98 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2GLO1
SCHEMBL27409367 0.98 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2GLO1
SCHEMBL18560335 0.98 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2GLO1
SCHEMBL24390490 0.98 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2GLO1
SCHEMBL2177917 0.98 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2GLO1
SCHEMBL27411240 0.98 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2GLO1
SCHEMBL24899341 0.98 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2GLO1
SCHEMBL18552085 0.98 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2GLO1
SCHEMBL12673653 0.98 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11084861-B2 GIP/GLP1 co-agonist compounds ELI LILLY AND COMPANY (US) 2021-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11084861-B2 GIP/GLP1 co-agonist compounds GLP1R, GIPR, GCGR GLP1R 1/4885NOD1 844/4885FOLH1 1092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback