SCHEMBL23733550

SCHEMBL23733550

NONC(=O)c1cccc(C=O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UNG P13051 1/20 0.58
HDAC3 O15379 3/20 0.44
HDAC1 Q13547 2/20 0.44
SRC P12931 1/20 0.44
TRIM24 O15164 1/20 0.42
TRIM33 Q9UPN9 1/20 0.42
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
ALDH1A1 P00352 5/20 0.40
NAT1 P18440 1/20 0.40
KDM4E B2RXH2 2/20 0.40
FURIN P09958 1/20 0.39
HDAC2 Q92769 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC4 P56524 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2284526 0.85 UNG (0.56) UNGHDAC3HDAC1SRCTRIM24
SCHEMBL9655260 0.82 UNG (0.61) UNGHDAC3HDAC1SRCTRIM24
SCHEMBL27703794 0.81 ALDH1A1 (0.65) UNGHDAC3HDAC1SRCTRIM24
SCHEMBL27210087 0.80 HDAC1 (0.65) UNGHDAC3HDAC1ALDH1A1KDM4E
SCHEMBL29957694 0.79 UNG (0.61) UNGHDAC3HDAC1SRCTRIM24
SCHEMBL62779 0.79 UNG (0.61) UNGHDAC3HDAC1SRCTRIM24
SCHEMBL2282647 0.79 UNG (0.49) UNGHDAC3HDAC1SRCTRIM24
SCHEMBL15652250 0.78 ERN1 (0.58) UNGHDAC3HDAC1SRCALDH1A1
SCHEMBL28000839 0.77 ALDH1A1 (0.59) UNGHDAC3HDAC1TRIM24TRIM33
SCHEMBL4680429 0.77 UNG (0.54) UNGHDAC3HDAC1SRCTRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11084262-B2 Polyamide composition and film and method for manufacturing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2021-08-10 US disclosed