Acetic Acid

Acetic Acid

SCHEMBL237341

CC(=O)O.OCCN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.58
LMNA P02545 2/20 0.56
ALDH1A1 P00352 1/20 0.56
ACHE P22303 1/20 0.56
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
HDAC1 Q13547 4/20 0.50
HDAC3 O15379 3/20 0.50
HDAC2 Q92769 3/20 0.50
HDAC8 Q9BY41 3/20 0.50
NCOR2 Q9Y618 2/20 0.50
HDAC4 P56524 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49
HDAC5 Q9UQL6 1/20 0.49
HSD17B10 Q99714 2/20 0.49
TSHR P16473 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122771 0.90 HTT (0.68) HTTLMNAALDH1A1ACHEMEN1
Propionic Acid SCHEMBL4176304 0.89 HTT (0.55) HTTLMNAALDH1A1ACHEMEN1
Hydrochloric Acid SCHEMBL6162321 0.88 HTT (0.66) HTTLMNAALDH1A1ACHEMEN1
SCHEMBL18379359 0.87 LMNA (0.52) HTTLMNAALDH1A1ACHEMEN1
SCHEMBL18546022 0.86 HTT (0.69) HTTLMNAALDH1A1ACHEMEN1
SCHEMBL9641405 0.86 HTT (0.69) HTTLMNAALDH1A1ACHEMEN1
SCHEMBL79747 0.86 HTT (0.62) HTTLMNAALDH1A1ACHEMEN1
SCHEMBL5672853 0.85 HTT (0.55) HTTLMNAALDH1A1ACHEMEN1
Butyric Acid SCHEMBL4185431 0.84 HTT (0.51) HTTLMNAALDH1A1ACHEMEN1
Alcohol SCHEMBL2794145 0.84 TSHR (0.58) HTTLMNAALDH1A1ACHEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264212-B1 ELEMENTS FOR FORMING PRINT-OUT IMAGES DU PONT (US) 2009-02-18 EP claimed
US-6869755-B2 Elements for forming print-out images E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-03-22 US claimed
EP-1264212-A2 ELEMENTS FOR FORMING PRINT-OUT IMAGES E. I. du Pont de Nemours and Company (US) 2002-12-11 EP claimed
US-20020146649-A1 Elements for forming print-out images E. I. DU PONT DE NEMOURS AND COMPANY 2002-10-10 US claimed
WO-2001067175-A2 ELEMENTS FOR FORMING PRINT-OUT IMAGES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2001-09-13 WO claimed
EP-2899592-A1 Coated substrate comprising a dual wavelength image-forming particulate composition and a process for making said composition INTERNATIONAL PAPER COMPANY (US) 2015-07-29 EP disclosed
US-20150185608-A1 IMAGING PARTICULATES, PAPER AND PROCESS, AND IMAGING OF PAPER USING DUAL WAVELENGTH LIGHT INTERNATIONAL PAPER COMPANY 2015-07-02 US disclosed
US-8980523-B2 Imaging particulates, paper and process, and imaging of paper using dual wavelength light INTERNATIONAL PAPER COMPANY (US) 2015-03-17 US disclosed
EP-2340463-B1 IMAGING PARTICULATE COMPOSITION AND IMAGING PROCESS USING DUAL WAVELENGTH LIGHT INT PAPER CO (US) 2014-12-17 EP disclosed
US-20140080044-A1 Imaging Particulates, Paper and Process, and Imaging of Paper Using Dual Wavelength Light INTERNATIONAL PAPER COMAPNY (US) 2014-03-20 US disclosed
US-8586279-B2 Imaging particulates, paper and process, and imaging of paper using dual wavelength light INTERNATIONAL PAPER COMPANY (US) 2013-11-19 US disclosed
US-20120003592-A1 IMAGING PARTICULATES, PAPER AND PROCESS, AND IMAGING OF PAPER USING DUAL WAVELENGTH LIGHT INTERNATIONAL PAPER COMAPNY (US) 2012-01-05 US disclosed
EP-0046271-B1 PHOTOSENSITIVE COMPOSITIONS AND ELEMENTS CONTAINING SUBSTITUTED HYDROXYLAMINE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-10-19 EP disclosed
EP-0046271-A1 Photosensitive compositions and elements containing substituted hydroxylamine E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-02-24 EP disclosed
US-4311783-A Dimers derived from unsymmetrical 2,4,5,-triphenylimidazole compounds as photoinitiators E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-01-19 US disclosed
US-4298678-A PHOTOOXIDANT AND LEUCO DYE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-03 US disclosed
EP-0024629-A2 Photoimaging composition comprising a 2,4,5-triphenylimidazolyl dimer and at least one compound selected from the group consisting of a leuco dye and a polymerizable ethylenically unsaturated monomer E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-11 EP disclosed
US-4252887-A HIGH SPEED IMAGING; PHOTOSENSITIVE TO LONGER WAVELENGTHS; USED WITH PHOTOPOLYMERIZABLE OLEFIN; OVERLAY FILMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-24 US disclosed
US-4078934-A Photosensitive, image-forming composition containing a leuco 2,3-disubstituted-1-indanone and a photooxidant E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-03-14 US disclosed
US-3992450-A PHOTOSENSITIVE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-16 US disclosed