Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237308 | 0.79 | LMNA (0.48) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL3237311 | 0.79 | LMNA (0.48) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL16297265 | 0.79 | LMNA (0.48) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL11829895 | 0.79 | AOC3 (0.48) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL7855317 | 0.79 | LMNA (0.54) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL28144387 | 0.78 | LMNA (0.57) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL15441563 | 0.78 | HTR2A (0.53) | LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL13458548 | 0.78 | HTR2A (0.53) | LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL10372161 | 0.76 | KDM4E (0.48) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| SCHEMBL4907724 | 0.75 | HTR2A (0.39) | RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4602074-A | SILICON CONTAINING ACRYLIC MONOMER | NIPPON CONTACT LENS MANUFACTURING LTD. (JP) | 1986-07-22 | — | — | US | claimed |
| US-8288496-B2 | Contact lens and its manufacturing method | NIPPON CONTACT LENS INC. (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110237701-A1 | CONTACT LENS AND ITS MANUFACTURING METHOD | NIPPON CONTACT LENS INC. (JP) | 2011-09-29 | — | — | US | disclosed |
| EP-2369370-A2 | Contact lens and its manufacturing method | Nippon Contact Lens Inc. (JP) | 2011-09-28 | — | — | EP | disclosed |
| US-4602074-A | SILICON CONTAINING ACRYLIC MONOMER | NIPPON CONTACT LENS MANUFACTURING LTD. (JP) | 1986-07-22 | — | — | US | disclosed |