⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787010 | 0.88 | — | — | |
| SCHEMBL24913318 | 0.84 | — | — | |
| SCHEMBL24913572 | 0.82 | — | — | |
| SCHEMBL24913466 | 0.81 | — | — | |
| SCHEMBL21787011 | 0.81 | — | — | |
| SCHEMBL23734272 | 0.81 | POLB (0.37) | — | |
| SCHEMBL24906032 | 0.81 | POLG (0.34) | — | |
| SCHEMBL23734492 | 0.79 | CA2 (0.33) | — | |
| SCHEMBL23734374 | 0.79 | CA2 (0.33) | — | |
| SCHEMBL21787207 | 0.79 | P2RY2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11085076-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-08-10 | — | — | US | disclosed |