Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 10/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19684575 | 0.82 | PNMT (0.47) | PNMTADRA2AADRA2BADRA2CCD44 | |
| SCHEMBL19684577 | 0.79 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2CCD44 | |
| SCHEMBL19684576 | 0.79 | PNMT (0.53) | PNMTADRA2AADRA2BADRA2CASIC3 | |
| SCHEMBL19684582 | 0.79 | PNMT (0.44) | PNMTADRA2AADRA2BADRA2CCD44 | |
| SCHEMBL15503204 | 0.79 | PNMT (0.49) | PNMTADRA2AADRA2BADRA2C | |
| Bromide SCHEMBL15515105 | 0.78 | PNMT (0.47) | PNMTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL29216547 | 0.78 | PNMT (0.49) | PNMTADRA2AADRA2BADRA2CCD44 | |
| SCHEMBL19684534 | 0.77 | PNMT (0.42) | PNMTADRA2AADRA2BADRA2CCD44 | |
| SCHEMBL15502998 | 0.77 | PNMT (0.42) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL20892025 | 0.77 | PNMT (0.42) | PNMTADRA2AADRA2BADRA2CCD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464249-B1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER (US) | 2021-08-11 | — | — | EP | disclosed |