SCHEMBL23735537

SCHEMBL23735537

CC(=O)NCCCCCC(=O)NCCCCNC(=O)CCCCCNC=O

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.57
MAPK1 P28482 1/20 0.57
HIF1A Q16665 1/20 0.57
ADRA1A P35348 1/20 0.56
PAOX Q6QHF9 3/20 0.48
CASP2 P42575 1/20 0.47
EPHX2 P34913 3/20 0.46
FAAH O00519 3/20 0.46
SLC6A5 Q9Y345 2/20 0.45
NAAA Q02083 1/20 0.44
EPHX1 P07099 1/20 0.44
ADH1B P00325 1/20 0.44
ADH1C P00326 1/20 0.44
ADH1A P07327 1/20 0.44
ADH4 P08319 1/20 0.44
ADH7 P40394 1/20 0.44
DNM1 Q05193 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23735535 0.98 KDM4E (0.55) KDM4EMAPK1HIF1AADRA1APAOX
SCHEMBL23735383 0.98 KDM4E (0.54) KDM4EMAPK1HIF1AADRA1APAOX
SCHEMBL31758415 0.94 KDM4E (0.50) KDM4EMAPK1HIF1AADRA1APAOX
SCHEMBL31758452 0.94 KDM4E (0.50) KDM4EMAPK1HIF1AADRA1APAOX
SCHEMBL23442125 0.89 KDM4E (0.73) KDM4EMAPK1HIF1AADRA1APAOX
SCHEMBL22811174 0.89 KDM4E (0.73) KDM4EMAPK1HIF1AADRA1APAOX
SCHEMBL27383468 0.87 KDM4E (0.68) KDM4EMAPK1HIF1AADRA1APAOX
SCHEMBL21695694 0.87 KDM4E (0.68) KDM4EMAPK1HIF1AADRA1APAOX
SCHEMBL23760291 0.86 CASP2 (0.47) CASP2EPHX2FAAHSLC6A5NAAA
SCHEMBL10380841 0.86 CASP2 (0.61) CASP2EPHX2FAAHSLC6A5NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3157978-B1 STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS SYMO CHEM B V (NL) 2021-08-11 EP disclosed