SCHEMBL23735557

SCHEMBL23735557

CC(=O)NNC(=O)CCC(=O)NNC=O

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.38
KDM4E B2RXH2 2/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23735559 0.92 KMT2A (0.43) NPSR1KDM4EMAPTKMT2ASMN1; SMN2
SCHEMBL182913 0.81
SCHEMBL14265339 0.75 KDM4E (0.39) NPSR1KDM4EKDM5CEGLN1PHF8
SCHEMBL8000409 0.75 HDAC3 (0.46) NPSR1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL18470774 0.75
SCHEMBL23735556 0.75 NPSR1 (0.33) NPSR1KDM4E
SCHEMBL12155314 0.74 KMT2A (0.53) NPSR1KDM4EMAPTKMT2ASMN1; SMN2
SCHEMBL16015581 0.73
SCHEMBL23987888 0.72 HSP90AA1 (0.52) NPSR1KDM4EMAPTKMT2AALDH1A1
SCHEMBL8423451 0.72 HDAC3 (0.52) NPSR1KDM4EMAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3157978-B1 STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS SYMO CHEM B V (NL) 2021-08-11 EP disclosed