SCHEMBL23735558

SCHEMBL23735558

CC(=O)NCCCCNC(=O)C(=O)NCCCCNC(C)=O

nearest known ligand 0.79

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.79
MAPK1 P28482 1/20 0.79
HIF1A Q16665 1/20 0.79
PAOX Q6QHF9 3/20 0.62
ADRA1A P35348 1/20 0.60
TSHR P16473 1/20 0.50
ALDH1A1 P00352 1/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
EPHX1 P07099 4/20 0.42
NAMPT P43490 1/20 0.42
FOLH1 Q04609 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL860791 0.91 KDM4E (0.94) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL6516953 0.88 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14739632 0.88 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL10937726 0.88 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14739904 0.88 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL1900654 0.88 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14740196 0.88 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL1847535 0.88 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14740132 0.88 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
Hexamethylenebisacetamide SCHEMBL61980 0.88 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3157978-B1 STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS SYMO CHEM B V (NL) 2021-08-11 EP disclosed