Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 9/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 6/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488793 | 0.69 | NQO1 (0.74) | SMN1; SMN2KDM4EHPGDNQO1LMNA | |
| SCHEMBL15201648 | 0.64 | NQO1 (0.64) | SMN1; SMN2KDM4EHPGDNQO1LMNA | |
| SCHEMBL13400766 | 0.63 | NQO1 (0.61) | SMN1; SMN2KDM4EHPGDNQO1LMNA | |
| SCHEMBL10062561 | 0.63 | LTA4H (0.63) | SMN1; SMN2HPGDNQO1LMNAALDH1A1 | |
| SCHEMBL11671912 | 0.63 | LTA4H (0.63) | SMN1; SMN2NQO1LMNAALDH1A1MAPT | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.62 | NQO1 (1.00) | SMN1; SMN2KDM4ENQO1ALDH1A1MAPT | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.62 | NQO1 (1.00) | SMN1; SMN2KDM4ENQO1ALDH1A1MAPT | |
| SCHEMBL24135044 | 0.62 | NQO1 (0.48) | SMN1; SMN2KDM4ENQO1LMNAGRM2 | |
| SCHEMBL3622807 | 0.62 | MEN1 (0.66) | SMN1; SMN2KDM4EHPGDNQO1LMNA | |
| SCHEMBL1390870 | 0.62 | NQO1 (0.67) | SMN1; SMN2KDM4EHPGDNQO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862003-A1 | AN SGLT-2 INHIBITOR FOR USE IN THE TREATMENT OF A METABOLIC DISORDER IN FELINE ANIMALS | Boehringer Ingelheim Vetmedica GmbH (DE) | 2021-08-11 | — | — | EP | disclosed |