SCHEMBL23735657

SCHEMBL23735657

COc1ccc(COC(=O)[C@H]2CCCN2C(=O)CCCCCOP(OCCC#N)N(C(C)C)C(C)C)c(OC)c1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 10/20 0.41
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 4/20 0.35
DPP4 P27487 1/20 0.35
HTR1A P08908 2/20 0.34
HTR7 P34969 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23735608 1.00 FKBP1A (0.41) FKBP1ATSHRMAPK1ALDH1A1DPP4
SCHEMBL23735605 1.00 FKBP1A (0.41) FKBP1ATSHRMAPK1ALDH1A1DPP4
SCHEMBL23735587 0.83 SPHK1 (0.37) FKBP1AHTR1AHTR7
SCHEMBL23735610 0.83 SPHK1 (0.37) FKBP1AHTR1AHTR7
SCHEMBL23735636 0.83 SPHK1 (0.37) FKBP1AHTR1AHTR7
SCHEMBL23920418 0.79 FKBP1A (0.50) FKBP1ATSHRMAPK1ALDH1A1DPP4
SCHEMBL23735628 0.76 SPHK1 (0.38) DPP4HTR1AHTR7
SCHEMBL23762248 0.74 DPP4 (0.41) FKBP1ADPP4
SCHEMBL23762230 0.74 DPP4 (0.41) FKBP1ADPP4
SCHEMBL20863812 0.74 DPP4 (0.41) FKBP1ADPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3862431-B1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES TORAY INDUSTRIES (JP) 2024-06-26 EP disclosed
US-20210317495-A1 METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULES TORAY INDUSTRIES, INC. (JP) 2021-10-14 US disclosed
EP-3862431-A1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES Toray Industries, Inc. (JP) 2021-08-11 EP disclosed