SCHEMBL23735950

SCHEMBL23735950

CCC(=O)CCC(=O)c1ccc(C(=O)CC)o1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
IAPP P10997 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.37
TDP1 Q9NUW8 2/20 0.35
HDAC4 P56524 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
MAPT P10636 4/20 0.34
KMT2A Q03164 3/20 0.34
GAA P10253 2/20 0.34
MEN1 O00255 2/20 0.34
KDM4E B2RXH2 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
TLR9 Q9NR96 1/20 0.34
CA9 Q16790 2/20 0.33
PLK1 P53350 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22328917 0.85 KDM4E (0.42) ALDH1A1SMN1; SMN2NPC1RAB9AIAPP
SCHEMBL19458019 0.85 MAPT (0.41) ALDH1A1SMN1; SMN2NPC1RAB9AL3MBTL1
SCHEMBL27441378 0.83 KMT2A (0.33) ALDH1A1SMN1; SMN2NPC1RAB9AIAPP
SCHEMBL23740096 0.81 IAPP (0.41) ALDH1A1SMN1; SMN2NPC1RAB9AIAPP
SCHEMBL19457972 0.79 HSD17B3 (0.48) ALDH1A1SMN1; SMN2IAPPL3MBTL1TDP1
SCHEMBL18403916 0.77 KMT2A (0.41) ALDH1A1SMN1; SMN2NPC1RAB9AL3MBTL1
SCHEMBL25869714 0.76 ERCC5 (0.32) ALDH1A1
SCHEMBL19457998 0.75 HSD17B3 (0.52) ALDH1A1IAPPMAPTKMT2AMEN1
SCHEMBL19458032 0.73 HSD17B3 (0.53) ALDH1A1MAPTKMT2AMEN1ATM
SCHEMBL953093 0.72 HPGD (0.53) ALDH1A1SMN1; SMN2NPC1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3862370-A1 POLYTETRAFLUOROETHYLENE PRODUCTION METHOD DAIKIN INDUSTRIES, LTD. (JP) 2021-08-11 EP disclosed