Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18403916 | 0.91 | KMT2A (0.41) | MAPTSMN1; SMN2L3MBTL1HDAC4HDAC6 | |
| SCHEMBL8743358 | 0.85 | CA9 (0.40) | MAPTSMN1; SMN2L3MBTL1ALDH1A1CA9 | |
| SCHEMBL953093 | 0.85 | HPGD (0.53) | MAPTSMN1; SMN2L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL23735950 | 0.85 | ALDH1A1 (0.45) | MAPTSMN1; SMN2L3MBTL1HDAC4HDAC6 | |
| SCHEMBL13181083 | 0.84 | ALDH1A1 (0.55) | MAPTSMN1; SMN2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL13078112 | 0.84 | NPC1 (0.47) | MAPTSMN1; SMN2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL19457972 | 0.82 | HSD17B3 (0.48) | SMN1; SMN2L3MBTL1HDAC4HDAC6ALDH1A1 | |
| SCHEMBL16312467 | 0.80 | HPGD (0.53) | L3MBTL1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL26696157 | 0.80 | ALDH1A1 (0.47) | MAPTSMN1; SMN2L3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL22328917 | 0.79 | KDM4E (0.42) | MAPTSMN1; SMN2L3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3231795-B1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | NINGBO INST MATERIALS TECH & ENG CAS (CN) | 2021-09-15 | — | — | EP | disclosed |
| US-10125110-B2 | Method for preparing 2,5-disubstituted furan compound | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2018-11-13 | — | — | US | disclosed |
| US-20170320844-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2017-11-09 | — | — | US | disclosed |
| EP-3231795-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | Ningbo Institute Of Material Technology And Engineering Chinese Academy of Sciences (CN) | 2017-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320844-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | ALOX5, PFAS, APEH | MAPT 4456/4885SMN1; SMN2 2174/4885L3MBTL1 4853/4885 |
| US-10125110-B2 | Method for preparing 2,5-disubstituted furan compound | ALOX5, PFAS, APEH | MAPT 4456/4885SMN1; SMN2 2174/4885L3MBTL1 4853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.