Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 6/20 | 0.34 |
| ▸ | CTSK | P43235 | 6/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23736274 | 0.92 | SMN1; SMN2 (0.39) | SMN1; SMN2CTSSCTSKNFKB1NFKB2 | |
| SCHEMBL15727271 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2CTSSCTSKNFKB1NFKB2 | |
| SCHEMBL23736344 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2CTSSCTSKNFKB1NFKB2 | |
| SCHEMBL7541004 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2CTSSCTSKNFKB1NFKB2 | |
| SCHEMBL28659964 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2CTSSCTSKNFKB1NFKB2 | |
| SCHEMBL15727250 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2CTSSCTSKNFKB1NFKB2 | |
| SCHEMBL1604541 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CTSSCTSKNFKB1NFKB2 | |
| SCHEMBL615910 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CTSSCTSKNFKB1NFKB2 | |
| SCHEMBL615909 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2CTSSCTSKNFKB1NFKB2 | |
| SCHEMBL15727246 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2CTSSCTSKNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922829-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-08-11 | — | — | EP | disclosed |