Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 11/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659964 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2NFKB1NFKB2RELACTSK | |
| SCHEMBL15727250 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2NFKB1NFKB2RELACTSK | |
| SCHEMBL3935052 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2NFKB1NFKB2RELACTSK | |
| SCHEMBL2241213 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2CTSKCTSSMAPTCTSL | |
| SCHEMBL25755437 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2CTSKCTSSMAPTCTSL | |
| SCHEMBL2241216 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2CTSKCTSSMAPTCTSL | |
| SCHEMBL15727271 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2NFKB1NFKB2RELACTSK | |
| SCHEMBL1604541 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2NFKB1NFKB2RELACTSK | |
| SCHEMBL615909 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2NFKB1NFKB2RELACTSK | |
| SCHEMBL615910 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2NFKB1NFKB2RELACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12358951-B2 | Cyclic peptide antibiotics | GENENTECH, INC. (US) | 2025-07-15 | — | — | US | disclosed |
| US-20230025834-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2023-01-26 | — | — | US | disclosed |
| US-20230025834-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2023-01-26 | — | — | US | disclosed |
| EP-4046996-A1 | CRYPTOPHYCIN COMPOUNDS AND CONJUGATES THEREOF | Universität Bielefeld (DE) | 2022-08-24 | — | — | EP | disclosed |
| CN-113710687-A | Cyclopeptide antibiotics | 豪夫迈·罗氏有限公司 | 2021-11-26 | — | — | CN | disclosed |
| WO-2020185999-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2020-09-17 | — | — | WO | disclosed |
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025834-A1 | CYCLIC PEPTIDE ANTIBIOTICS | NPPA, LNPEP, CLPP | SMN1; SMN2 3801/4885NFKB1 2768/4885NFKB2 2669/4885 |
| US-12358951-B2 | Cyclic peptide antibiotics | NPPA, LNPEP, CLPP | SMN1; SMN2 3801/4885NFKB1 2768/4885NFKB2 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.