SCHEMBL23736459

SCHEMBL23736459

CNC(=O)C(C)(C)N(C(C)C)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22044578 0.91 POLB (0.32) POLB
SCHEMBL16975853 0.74
SCHEMBL22044608 0.73 TSHR (0.42) POLB
SCHEMBL6284411 0.70
SCHEMBL14507715 0.70 CA12 (0.30)
SCHEMBL17447492 0.69 ALDH1A1 (0.32)
SCHEMBL33307 0.69 PIK3CD (0.32) POLB
SCHEMBL5537638 0.69 PIK3CD (0.32) POLB
SCHEMBL23738097 0.69 POLB (0.34) POLB
SCHEMBL17629667 0.69 PIK3CD (0.32) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3862023-A1 CONJUGATES OF CELL-BINDING MOLECULES WITH CYTOTOXIC AGENTS Hangzhou DAC Biotech Co, Ltd (CN) 2021-08-11 EP disclosed