SCHEMBL23738833

SCHEMBL23738833

c1ccc2c(c1)Oc1cc3c(cc1C21c2ccccc2-c2ccccc21)c1c2ccccc2ccc1n3-c1ccc2c(c1)oc1ccccc12

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23185062 0.97 TDP1 (0.31) TDP1L3MBTL1
SCHEMBL23739209 0.95 SIRT2 (0.31)
SCHEMBL23185064 0.93 SIRT2 (0.31)
SCHEMBL23184598 0.91
SCHEMBL23738908 0.89
SCHEMBL23739034 0.88 PTGER4 (0.30)
SCHEMBL21397919 0.87 TDP1 (0.33) TDP1L3MBTL1
SCHEMBL23185107 0.87 KDM4E (0.31) L3MBTL1
SCHEMBL23183925 0.87 PTGER4 (0.32)
SCHEMBL23738731 0.86 SIRT2 (0.32) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3388438-B1 SPIRO-STRUCTURED COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2021-08-11 EP disclosed