Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.38 |
| ▸ | NPY4R | P50391 | 5/20 | 0.38 |
| ▸ | NPY1R | P25929 | 4/20 | 0.38 |
| ▸ | NPY2R | P49146 | 2/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23739148 | 0.93 | SIRT2 (0.43) | SIRT2SIRT1NPY5RNPY4RNPY1R | |
| SCHEMBL20880254 | 0.93 | SIRT2 (0.39) | SIRT2SIRT1NPY5RNPY4RNPY1R | |
| SCHEMBL24253175 | 0.87 | SIRT2 (0.41) | SIRT2SIRT1NPY5RNPY4RNPY1R | |
| SCHEMBL20880212 | 0.87 | SIRT2 (0.44) | SIRT2SIRT1SIRT3 | |
| SCHEMBL24115692 | 0.87 | SIRT2 (0.37) | SIRT2SIRT1NPY5RNPY4RNPY1R | |
| SCHEMBL19841675 | 0.84 | NPY5R (0.39) | SIRT2SIRT1NPY5RNPY4RNPY1R | |
| SCHEMBL16646739 | 0.83 | NPY5R (0.39) | SIRT2SIRT1NPY5RNPY4RNPY1R | |
| SCHEMBL19522514 | 0.83 | NPY4R (0.42) | SIRT2SIRT1NPY5RNPY4RNPY1R | |
| SCHEMBL20015437 | 0.82 | NPY5R (0.40) | SIRT2SIRT1NPY5RNPY4RNPY1R | |
| SCHEMBL25765429 | 0.78 | NPY5R (0.40) | SIRT2SIRT1NPY5RNPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590541-B1 | DRUG-CONJUGATES AND USES THEREOF | CONCORTIS BIOSYSTEMS CORP (US) | 2021-08-11 | — | — | EP | disclosed |