Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44477 | 0.94 | NOS1 (0.51) | NOS1SMN1; SMN2GABRA5GABRB2HSD17B10 | |
| SCHEMBL9729165 | 0.92 | NOS1 (0.50) | NOS1SMN1; SMN2GABRA5GABRB2HSD17B10 | |
| SCHEMBL11588307 | 0.92 | NOS1 (0.50) | NOS1SMN1; SMN2GABRA5GABRB2HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28007740 | 0.92 | NOS1 (0.50) | NOS1SMN1; SMN2GABRA5GABRB2HSD17B10 | |
| SCHEMBL14643881 | 0.92 | NOS1 (0.50) | NOS1SMN1; SMN2GABRA5GABRB2HSD17B10 | |
| SCHEMBL3828155 | 0.92 | NOS1 (0.50) | NOS1SMN1; SMN2GABRA5GABRB2HSD17B10 | |
| Pyridine SCHEMBL27812107 | 0.88 | NOS1 (0.51) | NOS1SMN1; SMN2GABRA5GABRB2HSD17B10 | |
| SCHEMBL5911714 | 0.88 | — | — | |
| Pyridine SCHEMBL27812133 | 0.87 | NOS1 (0.50) | NOS1SMN1; SMN2GABRA5GABRB2HSD17B10 | |
| Toluene SCHEMBL27832196 | 0.87 | NOS1 (0.58) | NOS1SMN1; SMN2GABRA5GABRB2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648925-A | 5-(4-chlorophenylmethyl)-4-tert-butyl-2-aminothiazolehydrobromate chiral crystal structure and preparation method thereof | UNIV HUNAN | 2010-02-17 | — | — | CN | claimed |
| CN-101492426-A | Thiazole schiff base containing nitryl, preparation and uses thereof | UNIV HUNAN (CN) | 2009-07-29 | — | — | CN | claimed |
| CN-110279726-A | Composition and its application containing Saxifragaceae Herba Chrysosplenii delavayi extract | 嘉兴市爵拓科技有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-104903320-B | Nitrogen-containing heterocycle compound or its salt | 富士胶片株式会社 | 2018-11-13 | — | — | CN | disclosed |
| CN-108685911-A | 2-[(4- tertiary butyl thiazole -2- bases) Ya Anji ]Application of the thiazolin 4 one in pharmacy | 山东大学 | 2018-10-23 | — | — | CN | disclosed |
| CN-106032365-B | Benzal thiazolinone of 2 (base of thiazole 2) imino group 5 and preparation method and application | 湖南大学 | 2018-03-23 | — | — | CN | disclosed |
| CN-105985298-B | 2 [(base of 5 halogen thiazole 2) imino group] 5 benzal thiazolinones and preparation method and application | 湖南大学 | 2018-02-23 | — | — | CN | disclosed |
| CN-105026386-B | Antiviral compound | 弗·哈夫曼-拉罗切有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106032365-A | 2-(thiazol-2-yl)imino-5-(benzylidene)thiazolidin-4-one, and preparing method and applications thereof | 湖南大学 | 2016-10-19 | — | — | CN | disclosed |
| CN-105026386-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-04 | — | — | CN | disclosed |
| EP-1812433-B1 | IMIDAZO[4,5-B]PYRIDIN-2-ONE AND OXAZOLO[4,5-B]PYRIDIN-2-ONE COMPOUNDS AND ANALOGS THEREOF AS THERAPEUTIC COMPOUNDS | CANCER REC TECH LTD (GB) | 2015-07-22 | — | — | EP | disclosed |
| CN-1069882-A | The Compounds and methods for that suppresses HIV and correlated virus | MEDIVIR AB (CH) | 1993-03-17 | — | — | CN | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |
| US-4535081-A | Antiallergic and antiulcer 1-oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides and intermediates therefor | PFIZER INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4423048-A | Antiallergic and antiulcer 1-oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides and intermediates therefor | PFIZER INC. (US) | 1983-12-27 | — | — | US | disclosed |
| US-4414388-A | ANTIALLERGENS, ANTIULCER AGENTS | PFIZER INC. (US) | 1983-11-08 | — | — | US | disclosed |
| US-4321372-A | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides | PFIZER INC. (US) | 1982-03-23 | — | — | US | disclosed |
| US-4277396-A | FOR POLYACRYLONITRILE AND ACID-MODIFIED POLYAMIDES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | disclosed |
| US-4104268-A | POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |