Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.63 |
| ▸ | CCR9 | P51686 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15742442 | 0.94 | DGAT1 (0.62) | DGAT1MAPT | |
| SCHEMBL14136900 | 0.91 | DGAT1 (0.59) | DGAT1MAPTKCNH2 | |
| SCHEMBL23740109 | 0.89 | DGAT1 (0.81) | DGAT1CCR9 | |
| SCHEMBL15732794 | 0.86 | DGAT1 (0.75) | DGAT1MAPT | |
| SCHEMBL14136848 | 0.83 | DGAT1 (0.59) | DGAT1MAPT | |
| SCHEMBL15742574 | 0.83 | DGAT1 (0.80) | DGAT1 | |
| SCHEMBL15522153 | 0.82 | DGAT1 (0.79) | DGAT1 | |
| SCHEMBL14136659 | 0.79 | DGAT1 (0.56) | DGAT1MAPT | |
| SCHEMBL20992139 | 0.78 | DGAT1 (0.53) | DGAT1 | |
| SCHEMBL15733006 | 0.78 | DGAT1 (0.55) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492474-B1 | INTERMEDIATES USED IN THE PRODUCTION OF DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2021-08-11 | — | — | EP | disclosed |