Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 20/20 | 0.58 |
| ▸ | WNT1 | P04628 | 12/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23741588 | 0.95 | DYRK1A (0.62) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23740780 | 0.90 | GSK3B (0.53) | GSK3BDYRK1AWNT1 | |
| SCHEMBL24219510 | 0.90 | GSK3B (0.47) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23741160 | 0.88 | ABL1 (0.51) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23740792 | 0.87 | DYRK1A (0.60) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23741017 | 0.87 | GSK3B (0.55) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23741058 | 0.86 | GSK3B (0.61) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23740948 | 0.86 | GSK3B (0.59) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23740986 | 0.85 | GSK3B (0.58) | GSK3BDYRK1AWNT1 | |
| SCHEMBL23741134 | 0.85 | GSK3B (0.56) | GSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448838-B1 | ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | BIOSPLICE THERAPEUTICS INC (US) | 2021-08-11 | — | — | EP | disclosed |