Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202927 | 0.77 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL17233310 | 0.74 | EPHX1 (0.37) | EPHX1 | |
| SCHEMBL24351984 | 0.73 | EPHX1 (0.42) | EPHX1 | |
| SCHEMBL23740830 | 0.72 | WNT1 (0.34) | EPHX1 | |
| SCHEMBL18459259 | 0.71 | EPHX1 (0.34) | EPHX1 | |
| SCHEMBL18416950 | 0.71 | EPHX1 (0.34) | EPHX1 | |
| SCHEMBL14654274 | 0.71 | EPHX1 (0.41) | EPHX1 | |
| SCHEMBL17286054 | 0.70 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL17285940 | 0.70 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL23741104 | 0.69 | CYP2D6 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3448838-B1 | ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | BIOSPLICE THERAPEUTICS INC (US) | 2021-08-11 | — | — | EP | disclosed |