Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12467653 | 0.84 | KMT2A (0.55) | KMT2APOLBSMN1; SMN2PKMMEN1 | |
| SCHEMBL23742755 | 0.81 | KMT2A (0.53) | KMT2APOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6757230 | 0.79 | KMT2A (0.60) | KMT2APOLBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL11633661 | 0.78 | KMT2A (0.59) | KMT2APOLBSMN1; SMN2PKMMEN1 | |
| SCHEMBL9598927 | 0.77 | KMT2A (0.58) | KMT2APOLBSMN1; SMN2PKMMEN1 | |
| SCHEMBL9569990 | 0.77 | KMT2A (0.58) | KMT2APOLBSMN1; SMN2PKMMEN1 | |
| SCHEMBL31285649 | 0.77 | KMT2A (0.58) | KMT2APOLBKDM4ESMN1; SMN2PKM | |
| SCHEMBL25160282 | 0.77 | MAPT (0.55) | KMT2APOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4594659 | 0.77 | KMT2A (0.58) | KMT2APOLBKDM4ESMN1; SMN2PKM | |
| SCHEMBL8974007 | 0.76 | KMT2A (0.63) | KMT2APOLBALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246122-A1 | Triazine Compounds and Uses Thereof | Aduro Biotech, Inc. (US) | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246122-A1 | Triazine Compounds and Uses Thereof | IL5, IL15, TLR5 | KMT2A 1303/4885POLB 4466/4885ALDH1A1 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.