Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757230 | 0.85 | KMT2A (0.60) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL4594659 | 0.83 | KMT2A (0.58) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL31285649 | 0.83 | KMT2A (0.58) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL9598927 | 0.83 | KMT2A (0.58) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL9720977 | 0.82 | KMT2A (0.64) | KMT2APOLBNPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL27175132 | 0.82 | KMT2A (0.61) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL8974007 | 0.82 | KMT2A (0.63) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL10038839 | 0.81 | DDAH1 (0.59) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL9721042 | 0.81 | KMT2A (0.62) | KMT2APOLBNPC1RAB9AMEN1 | |
| SCHEMBL12467653 | 0.81 | KMT2A (0.55) | KMT2APOLBNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270322-A | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
| EP-0555825-A1 | Imidazo(1,2-a)pyridines as angiotensin-II-antagonists | Dr. Karl Thomae GmbH (DE) | 1993-08-18 | — | — | EP | disclosed |