Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.35 |
| ▸ | GLP1R | P43220 | 8/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23743173 | 1.00 | KDM4E (0.40) | KDM4EHSD17B10NPC1MAPTRAB9A | |
| SCHEMBL25664162 | 0.86 | GLP1R (0.43) | KDM4EHSD17B10NPC1MAPTRAB9A | |
| SCHEMBL25595600 | 0.85 | GLP1R (0.43) | KDM4EHSD17B10NPC1MAPTRAB9A | |
| SCHEMBL25595599 | 0.85 | GLP1R (0.43) | KDM4EHSD17B10NPC1MAPTRAB9A | |
| SCHEMBL23743174 | 0.82 | KDM4E (0.40) | KDM4EHSD17B10NPC1MAPTRAB9A | |
| SCHEMBL16093019 | 0.79 | GLP1R (0.41) | NOD1C3AR1GLP1RALB | |
| SCHEMBL27105920 | 0.78 | TDP1 (0.44) | KDM4EHSD17B10NPC1MAPTRAB9A | |
| SCHEMBL13599221 | 0.78 | TDP1 (0.44) | KDM4EHSD17B10NPC1MAPTRAB9A | |
| SCHEMBL13599224 | 0.78 | TDP1 (0.44) | KDM4EHSD17B10NPC1MAPTRAB9A | |
| SCHEMBL16093004 | 0.77 | GLP1R (0.37) | HSD17B10NOD1C3AR1GLP1RALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210244824-A1 | POLYPEPTIDE CONJUGATES FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS | OHIO STATE INNOVATION FOUNDATION | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210244824-A1 | POLYPEPTIDE CONJUGATES FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS | LNPEP, PCNP, NASP | KDM4E 4478/4885HSD17B10 4307/4885NPC1 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.