SCHEMBL23743992

SCHEMBL23743992

C[C@H]1O[C@@H](n2cc(C(N)=O)c3c(N)ncnc32)C[C@@H]1O

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADK P55263 11/20 0.65
NPC1 O15118 1/20 0.43
GALR3 O60755 1/20 0.43
S1PR4 O95977 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
S1PR1 P21453 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
PAX8 Q06710 1/20 0.43
METTL3 Q86U44 3/20 0.42
CA2 P00918 2/20 0.41
PRMT5 O14744 2/20 0.40
HASPIN Q8TF76 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23745918 0.90 NPC1 (0.55) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL23950074 0.86 ADK (0.59) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL23943037 0.86 ADK (0.53) ADKMETTL3PRMT5
SCHEMBL24127868 0.84 ADK (0.54) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL23745928 0.84 ADK (0.54) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL23743999 0.84 ADK (0.54) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL23743998 0.81 ADK (0.61) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL6469013 0.79 ADK (1.00) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL6731807 0.78 ADK (0.60) ADKNPC1GALR3S1PR4ALDH1A1
SCHEMBL1737471 0.78 ADK (0.60) ADKNPC1GALR3S1PR4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021211759-A1 METHOD FOR TREATING POXVIRIDAE INFECTIONS OYAGEN, INC. (US) 2021-10-21 WO disclosed
WO-2021211757-A1 METHOD FOR TREATING ARENAVIRIDAE INFECTIONS OYAGEN, INC. (US) 2021-10-21 WO disclosed
WO-2021158248-A1 METHOD FOR TREATING CORONAVIRUS INFECTIONS OYAGEN, INC. (US) 2021-08-12 WO disclosed
WO-2021158701-A1 METHOD FOR TREATING CORONAVIRUS INFECTIONS OYAGEN, INC. (US) 2021-08-12 WO disclosed