Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 11/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26429325 | 1.00 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CHRM5GPR119 | |
| SCHEMBL26429326 | 1.00 | CHRM2 (0.46) | CHRM2CHRM1CHRM3CHRM5GPR119 | |
| SCHEMBL26429782 | 0.93 | GPR119 (0.41) | CHRM2CHRM1CHRM3CHRM5GPR119 | |
| SCHEMBL26429752 | 0.93 | CHRM2 (0.47) | CHRM2CHRM1CHRM3CHRM5GPR119 | |
| SCHEMBL26429409 | 0.91 | CHRM4 (0.44) | CHRM2CHRM1CHRM3CHRM5GPR119 | |
| SCHEMBL26429793 | 0.90 | GPR119 (0.53) | CHRM2CHRM1CHRM3GPR119CHRM4 | |
| SCHEMBL30345592 | 0.90 | GPR119 (0.53) | CHRM2CHRM1CHRM3GPR119CHRM4 | |
| SCHEMBL26429324 | 0.89 | CHRM2 (0.47) | CHRM2CHRM1CHRM3CHRM5GPR119 | |
| SCHEMBL26429319 | 0.88 | CHRM1 (0.59) | CHRM2CHRM1CHRM3CHRM5CHRM4 | |
| SCHEMBL26429304 | 0.88 | CHRM2 (0.45) | CHRM2CHRM1CHRM3CHRM5GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158698-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |