Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12582122 | 0.88 | BRD4 (0.45) | BRD4HDAC6HDAC3HDAC1HDAC8 | |
| SCHEMBL23815542 | 0.85 | BRD4 (0.43) | BRD4HDAC6HDAC3HDAC1HDAC8 | |
| SCHEMBL23815596 | 0.85 | BRD4 (0.43) | BRD4HDAC6HDAC3HDAC1HDAC8 | |
| SCHEMBL23745079 | 0.83 | CHEK2 (0.47) | BRD4HDAC6HDAC3PKN1PKN2 | |
| SCHEMBL26242966 | 0.81 | CHEK2 (0.48) | BRD4HDAC6HDAC3PKN1PKN2 | |
| SCHEMBL23745062 | 0.78 | RAB9A (0.51) | BRD4HDAC6HDAC3PKN1PKN2 | |
| SCHEMBL23815696 | 0.76 | HDAC6 (0.39) | BRD4HDAC6HDAC3HDAC1HDAC8 | |
| SCHEMBL23815771 | 0.76 | HDAC6 (0.39) | HDAC6HDAC3HDAC1HDAC8PKN1 | |
| SCHEMBL25697848 | 0.76 | HDAC6 (0.39) | HDAC6HDAC3HDAC1HDAC8PKN1 | |
| SCHEMBL23682632 | 0.75 | HDAC6 (0.42) | BRD4HDAC6HDAC3HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158707-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2021-08-12 | — | — | WO | disclosed |