Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29294034 | 0.86 | TSHR (0.32) | TSHRPOLBGAAMAPTTDP1 | |
| SCHEMBL18677688 | 0.78 | TSHR (0.39) | TSHRPOLBGAAMAPTTDP1 | |
| SCHEMBL6897046 | 0.77 | MAPT (0.34) | TSHRPOLBGAAMAPTTDP1 | |
| SCHEMBL14140317 | 0.77 | STING1 (0.32) | — | |
| SCHEMBL21955598 | 0.77 | — | — | |
| SCHEMBL15183842 | 0.76 | TSHR (0.41) | TSHRPOLBGAAMAPTTDP1 | |
| SCHEMBL8381586 | 0.76 | TSHR (0.35) | TSHRPOLBGAAMAPTTDP1 | |
| SCHEMBL24168564 | 0.74 | ALDH1A1 (0.42) | TSHRALDH1A1 | |
| SCHEMBL23008645 | 0.74 | ALDH1A1 (0.35) | GAAALDH1A1 | |
| SCHEMBL9669221 | 0.73 | TSHR (0.38) | TSHRPOLBGAAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158707-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. (US) | 2021-08-12 | — | — | WO | disclosed |