Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29197662 | 1.00 | CTSL (0.50) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL1928095 | 0.91 | TSHR (0.58) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL17019782 | 0.91 | TSHR (0.58) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL15642921 | 0.90 | CTSL (0.48) | CTSLCTSBCTSKTSHRTAAR1 | |
| Hydrochloric Acid SCHEMBL15258725 | 0.88 | CTSL (0.47) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL5526821 | 0.86 | CTSL (0.50) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL16398142 | 0.86 | CTSL (0.50) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL5526823 | 0.86 | CTSL (0.50) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL5006985 | 0.84 | TSHR (0.50) | CTSLCTSBCTSKTSHRTAAR1 | |
| SCHEMBL5006990 | 0.84 | TSHR (0.50) | CTSLCTSBCTSKTSHRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283610-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2021158634-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |