Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 19/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 11/20 | 0.45 |
| ▸ | MMP2 | P08253 | 9/20 | 0.45 |
| ▸ | MMP13 | P45452 | 4/20 | 0.45 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.44 |
| ▸ | MMP14 | P50281 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745272 | 0.86 | ADAMTS5 (0.61) | ADAMTS5ADAM17MMP2MMP13ADAMTS1 | |
| SCHEMBL23745246 | 0.86 | ADAMTS5 (0.61) | ADAMTS5ADAM17MMP2MMP13ADAMTS1 | |
| SCHEMBL23745245 | 0.86 | ADAMTS5 (0.61) | ADAMTS5ADAM17MMP2MMP13ADAMTS1 | |
| SCHEMBL23745276 | 0.83 | ADAMTS5 (0.45) | ADAMTS5ADAM17MMP2MMP13ADAMTS1 | |
| SCHEMBL23727492 | 0.77 | ADAMTS5 (0.52) | ADAMTS5ADAM17MMP2MMP13ADAMTS1 | |
| SCHEMBL23727601 | 0.77 | ADAMTS5 (0.69) | ADAMTS5ADAM17MMP2MMP13ADAMTS1 | |
| SCHEMBL23745259 | 0.76 | ADAMTS5 (0.43) | ADAMTS5ADAM17MMP2MMP13ADAMTS1 | |
| SCHEMBL23745269 | 0.76 | ADAMTS5 (0.43) | ADAMTS5ADAM17MMP2MMP13ADAMTS1 | |
| SCHEMBL23745271 | 0.76 | ADAMTS5 (0.43) | ADAMTS5ADAM17MMP2MMP13ADAMTS1 | |
| SCHEMBL23745265 | 0.75 | ADAMTS5 (0.55) | ADAMTS5ADAM17MMP2MMP13ADAMTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |