Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 17/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.48 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745393 | 0.81 | ADAMTS5 (0.47) | ADAMTS5ADAMTS4 | |
| SCHEMBL30012317 | 0.78 | ADAMTS5 (0.62) | ADAMTS5ADAM17ADAMTS4 | |
| SCHEMBL31121178 | 0.78 | ADAMTS5 (0.62) | ADAMTS5ADAM17ADAMTS4 | |
| SCHEMBL31121193 | 0.78 | ADAMTS5 (0.62) | ADAMTS5ADAM17ADAMTS4 | |
| SCHEMBL23745389 | 0.78 | ADAMTS5 (0.62) | ADAMTS5ADAM17ADAMTS4 | |
| SCHEMBL23745337 | 0.78 | ADAMTS5 (0.62) | ADAMTS5ADAM17ADAMTS4 | |
| SCHEMBL23745397 | 0.78 | ADAMTS5 (0.62) | ADAMTS5ADAM17ADAMTS4 | |
| SCHEMBL23728027 | 0.78 | ADAMTS5 (0.62) | ADAMTS5ADAM17ADAMTS4 | |
| SCHEMBL23745417 | 0.76 | ADAMTS5 (0.67) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 | |
| SCHEMBL3787633 | 0.75 | HTR2A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158626-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2021-08-12 | — | — | WO | disclosed |