Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | CCR9 | P51686 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747092 | 0.88 | FFAR4 (0.44) | FFAR4SMN1; SMN2TP53ALDH1A1MAPK1 | |
| SCHEMBL23746996 | 0.84 | KIT (0.42) | FFAR4SMN1; SMN2ALDH1A1EGFRKDR | |
| SCHEMBL23747093 | 0.82 | FFAR4 (0.39) | FFAR4SMN1; SMN2TP53ALDH1A1MAPK1 | |
| SCHEMBL23746994 | 0.80 | EGFR (0.45) | FFAR4SMN1; SMN2ALDH1A1EGFRKDR | |
| SCHEMBL23746992 | 0.73 | EGFR (0.42) | EGFRKDR | |
| SCHEMBL23747000 | 0.73 | EGFR (0.47) | ALDH1A1EGFRKDR | |
| SCHEMBL23746998 | 0.72 | EGFR (0.47) | ALDH1A1EGFRKDR | |
| SCHEMBL23747019 | 0.71 | EGFR (0.47) | PTGDR2EGFRKDR | |
| SCHEMBL7587082 | 0.70 | FFAR4 (0.71) | FFAR4SMN1; SMN2TP53HDAC1HDAC8 | |
| SCHEMBL9044998 | 0.70 | PTGDR2 (0.52) | FFAR4TP53ALDH1A1PTGDR2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158516-A1 | IRE1α MODULATORS AND USES THEREOF | NIMBUS IASO, INC. (US) | 2021-08-12 | — | — | WO | disclosed |