Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CCR4 | P51679 | 3/20 | 0.44 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747082 | 0.85 | CCR4 (0.46) | PTGDR2MEN1KMT2ACCR4EDNRA | |
| SCHEMBL23747000 | 0.85 | EGFR (0.47) | EGFRKDRKMT2AEDNRAEDNRB | |
| SCHEMBL23746994 | 0.83 | EGFR (0.45) | EGFRKDRCCR4LMNATSHR | |
| SCHEMBL23746998 | 0.81 | EGFR (0.47) | EGFRKDRMEN1KMT2AGAA | |
| SCHEMBL23747098 | 0.80 | ALDH1A1 (0.49) | EGFRKDRKMT2ANR1I2TSHR | |
| SCHEMBL23746990 | 0.79 | PTGDR2 (0.43) | EGFRKDRPTGDR2MEN1KMT2A | |
| SCHEMBL23747097 | 0.74 | KDM4E (0.47) | EGFRKDRKMT2A | |
| SCHEMBL23746986 | 0.72 | EGFR (0.44) | EGFRKDREDNRAEDNRBGAA | |
| SCHEMBL23746995 | 0.71 | FKBP1A (0.43) | EGFRKDRKMT2ALMNAHSD17B10 | |
| SCHEMBL23746997 | 0.70 | EGFR (0.43) | EGFRKDRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158516-A1 | IRE1α MODULATORS AND USES THEREOF | NIMBUS IASO, INC. (US) | 2021-08-12 | — | — | WO | disclosed |