Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 12/20 | 0.58 |
| ▸ | CDK12 | Q9NYV4 | 12/20 | 0.58 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.58 |
| ▸ | CDK9 | P50750 | 11/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.58 |
| ▸ | CDK2 | P24941 | 9/20 | 0.58 |
| ▸ | CDK7 | P50613 | 13/20 | 0.49 |
| ▸ | CCNH | P51946 | 13/20 | 0.49 |
| ▸ | MNAT1 | P51948 | 12/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25596344 | 0.80 | CCNT1 (0.60) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL19462177 | 0.77 | CCNK (0.55) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL23197829 | 0.77 | IDH2 (0.45) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL23003167 | 0.76 | CCNK (0.56) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL23003170 | 0.76 | CCNK (0.56) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL13693348 | 0.74 | BRD4 (0.52) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL22895378 | 0.74 | CCNT1 (0.50) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL13524818 | 0.74 | BRD4 (0.52) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL23002957 | 0.73 | CCNK (0.56) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL23002959 | 0.73 | CCNK (0.56) | CCNKCDK12CCNT1CDK9CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158516-A1 | IRE1α MODULATORS AND USES THEREOF | NIMBUS IASO, INC. (US) | 2021-08-12 | — | — | WO | disclosed |